Women can often experience vaginal atrophy associated with the thinning of vaginal tissues and dryness due to declining levels of oestrogen with the onset of the menopause and following some medical interventions. These symptoms can be significantly eased through the use of an appropriate vaginal moisturiser/lubricant. The JN Femme product, Revitalise, effectively moisturises and eliminates dryness and discomfort and the company are committed to a scientific approach and required scientific data to help prove the effectiveness of their product in combating the discomfort of dryness experienced by many women.
Shannon ABC have significant experience in human tissue cell culture, and the use of this tool to support industry and commercial challenges. A researcher was assigned to this project, directed by the Principal Investigator. A new tissue relevant cell line mimicking the lower female reproductive tract was established in Shannon ABC for the purposes of this project. Dryness and irritation activity was induced in this cell line, and the ability of JN Femme’s product to mediate these biological activities was assessed. Based on biomarker activity in the cell tissue model, it was determined that the product had both anti-irritant and hydration properties.
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